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All About Tramadol Tramadol is an opioid pain medication . It is available in the market with the brand name Ultram among others. It is also available in combination with acetaminophen (paracetamol) or as longer-acting formulations. On a dosage-to-dosage basis, it has about one-tenth of the potency of morphine and is equally potent to pethidine and codeine. Tramadol is useful in relieving moderate to moderately severe pain. It helps manage severe pain enough to require an opioid analgesic and for which alternative treatments are inadequate. It is also available in injection along with oral tablets/ capsules and liquid. There is moderate evidence of its use as a second-line treatment for fibromyalgia as a secondary painkiller. Tramadol is a medicine that works in the brain to change how your body responds to pain and how your body feels. It starts its work of relieving the pain within an hour when you take the immediate-release formulation within an ho...